The Varsinais-Suomi Regional Fund was founded in 1964 and is one of the Finnish Cultural Foundation's 17 regional funds. The Fund provides grants and awards to local people active in the arts, the sciences, and other fields of endeavour and to scientific or artistic work carried out in or covering one or more of the region's 27 municipalities.

The Varsinais-Suomi Regional Fund comprises a Genral Fund and donation- and bequest-based donor funds. Grants made from the latter are directed towards areas specified by the donor when making his or her bequest. Areas not covered by this procedure are supported from the general funds.

The Fund's activities and decision-making are impartial and not linked to political parties or other organisations or associations. Grants made by the Fund are decided by an Administrative Council representing a wide range of expertise and knowledge in the arts, the sciences, society, and business in the region.