The Häme Regional Fund was founded in 1960 and is one of the Finnish Cultural Foundation's 17 regional funds. The Fund is devoted to promoting and developing the arts, the sciences, and other fields of endeavour in the region - by providing annual grants and awards. Applicants born in the region are given priority when making grants, as is scientific or artistic work carried out in or covering the region. The Fund covers 13 municipalities, of which some are shared with the Pirkanmaa Regional Fund.

The Häme Regional Fund comprises a General Fund and donation- and bequest-based donor funds. Grants made from the latter are directed towards areas specified by the donor when making his or her bequest. Areas not covered by this procedure are supported from the general funds.

The Fund's activities and decision-making are impartial and not linked to political parties or other organisations or associations. Grants made by the Fund are decided by an Administrative Council representing a wide range of expertise and knowledge in the arts, the sciences, society, and business in the region.